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محصولات
Principles of Tissue Engineering Fifth Edition - Original PDF
نویسندگان: خلاصه: Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production – is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field.
Zufallsbefunde in der Skelettradiologi - Original PDF
نویسندگان: خلاصه: Vorwort Die sich in der Radiologie schon längst etablierte und ständig weiter zunehmende Bilderflut sowie die Modalitäten und Erfolge der Krebstherapien mit ausgedehnten prätherapeutischen und langfristigen Nachsorgeuntersuchungen führen zwangsläufig zur Aufdeckung von immer mehr Zufalls- und Nebenbefunden, die vor allem dem Nichtspezialisten in der Skelettradiologie erhebli- che interpretatorische Probleme bereiten können. Doch wie geht man damit um? Sicherlich nicht, indem man die Bilderflut durch mehr oder weniger ungezielte zusätzliche Unter- suchungsverfahren ausweitet und damit unter Umständen neue Zufallsbefunde kreiert. Das gilt besonders für hoch sensitive aber weniger spezifische Modalitäten. Der anspruchsvolle und präzise Radiologe wird vielmehr ein ergänzendes Verfahren einsetzen, das – an der anatomischen Struktur des Zufallsbefunds orientiert – eine höhere Spezifität besitzt und zu einer begründeten und klinisch brauchbaren Diagnose führt. Der häufig angewendete Trick, sich der Verantwortung zu entziehen und eine histologi- sche Abklärung zu empfehlen, sollte gemieden werden. Denn die histologische Interpretation des Pathologen kann in der Skelett- radiologie nur so gut sein, wie der radiologische Befund klar und richtungsweisend ist. Ich betätige mich seit vielen Jahren als Konsiliarius in der Ske- lettradiologie. Das eingesandte Krankengut besteht zu etwa 50 % aus klinisch asymptomatischen Zufallsbefunden, hinter denen benigne Knochentumoren und tumorähnliche Läsionen, Erkran- kungen im Frühstadium, Teile einer systemischen Erkrankung, ungewöhnliche Normvarianten und vieles mehr stecken können. Es wird an mehr als 160 Fällen und fast 100 differenzialdiag- nostisch passenden Kasuistiken aufgezeigt, wie man professionell an solche Befunde unter Einbeziehung der individuellen Situation des Patienten herangeht, welche Relevanz sie haben und welche sinnvollen Empfehlungen man zum weiteren Prozedere geben kann. Mein Dank für die Überlassung der besonderen Fälle gilt den Kollegen CA Dr. med. Jürgen Wiens, Wolfsburg (Fall 22), Dr. med. Thomas Grieser, Augsburg (Fall 30), Professor Dr. med. Michael Laniado, Dresden (Fälle 34, 61), Privt.-Doz. Dr. Sönke Langner, Greifswald (Fall 45) und CA Dr. med. Nils H. Goecke, Wildes- hausen (Fall 131).
Radiologische Diagnostik Abdomen und Thorax - Original PDF
نویسندگان: خلاصه: Ultraschall, CT (Computertomografie) und MRT (Magnetreso- nanztomografie) sind die wichtigsten Modalitäten zur Unter- suchung der Kopf-Hals-Region. Gemäß den Leitlinien der Deut- schen Röntgengesellschaft (AG Kopf-Hals-Diagnostik) wird die MRT bei Verdacht auf suprahyoidale Tumoren aufgrund ihres gu- ten Weichteilkontrasts eingesetzt. Die CT kommt bei infrahyoidal gelegenen Tumoren zur Anwendung, da sie aufgrund der gerin- gen Untersuchungszeit im Vergleich zur MRT deutlich weniger artefaktanfällig ist. ●HMerke Bei der CT führt ein langes Zeitintervall nach Kontrastmittelinjek- tion (60–80 s) zur besseren Darstellung von Tumoren. Für die MRT ist gemäß den Empfehlungen der AG Kopf-Hals- Diagnostik der Deutschen Röntgengesellschaft die Durchführung mindestens folgender Sequenzen erforderlich: ● koronare fettunterdrückte T2w (T2-gewichtete) Sequenz (STIR [Short-Tau Inversion-Recovery]) mit einer Schichtdicke von 3–5 mm ● axiale T2w Sequenz mit Fettunterdrückung mit einer Schicht- dicke von 3–4 mm ● axiale und koronare native T1w (T1-gewichtete) SE-Sequenz (Spin-Echo-Sequenz) ohne Fettsättigung mit einer Schichtdicke von 3–4 mm ● axiale und koronare fettunterdrückte T1w SE-Sequenz nach i. v. (intravenöser) Kontrastmittelinjektion
Synthetic Polymers for Biotechnology and Medicine - Original PDF
نویسندگان: خلاصه: One of the most powerful group of chemicals in the body are organic compounds collectively referred to as hormones. The glands responsible for the production and release of hormones comprise the endocrine system. Endocrine activities have been identified in certain organs, such as the heart, kidneys, duodenum, liver and the islets of Langerhans in the pancreas (which contains the insulin gland), which are normally associated with other system functions. There have been numerous attempts to replace organ function using cell transplantation including direct injections of dissociated cells into organs such as the liver, kidney or spleen.1-5 Subcutaneous and intraperitoneal routes have also been evaluated.6-10 More recent investigations have applied extracellular matrix polymers as structural supports for cell transplantation and immunoprotection.11,12 Potential medical applications of such “artificial cells” or “tissue engineered” organoids include an extracorporeal bioartificial liver for detoxification,2 artificial red blood substitutes,13 the extracorporeal artificial kidney for hemodialysis,14 immunosorbents15 and drug delivery systems.16The transplantation of immunoisolated (microencapsulated) cells represents another emerging area in biotechnology research and commercialization. Under such a scenario, the encapsulated cells, which could be a xenograft, would be hidden from the immune system of the body, but would still be able to respond to extracellular stimuli (e.g., blood glucose), with the required hormone, in the case of diabetes therapy insulin, secreted into the systemic circulation. Other applications of the microencapsulation concept include the encapsulation of genetically modified cells, which represents a novel approach to somatic gene therapy.17 This chapter will review recent advances in cell encapsulation from material science, technological and tissue-related perspectives. Cell coating, microencapsulation devices and bioartificial organs will be discussed with the artificial pancreas and treatment of diabetes used as a case study denominator throughout the review.
Artificial Intelligence in Medicine: Joint European Conference on Artificial Intelligence in Medicine and Medical Decision Making, AIMDM'99 Aalborg, Denmark, June 20–24, 1999 Proceedings - Original PDF
نویسندگان: خلاصه: Updates pregnancy-specific measurement instruments for examining maternal psychosocial status Discusses substantial research on maternal prenatal stress and high-risk pregnancy This book constitutes the refereed proceedings of the Joint European Conference on Artificial Intelligence in Medicine and Medical Decision Making, AIMDM'99, held in Aalborg, Denmark, in June 1999. The 27 full papers and 19 short papers presented in the book together with four invited papers were selected from 90 submissions. The papers are organized in topical sections on guidelines and protocols; decision support systems, knowledge-based systems, and cooperative systems; model-based systems; neural nets and causal probabilistic networks; knowledge representation; temporal reasoning; machine learning; natural language processing; and image processing and computer aided design.
Social Trauma – An Interdisciplinary Textbook - Original PDF
نویسندگان: خلاصه: An interdisciplinary reference on clinical and social theories of trauma Bridges theoretical and clinical issues pertaining to traumatic experiences Addresses related areas such as legal aspects, memory, and developmental psychology
Making Space for Justice: Social Movements, Collective Imagination, and Political Hope - Original PDF
نویسندگان: خلاصه: From nineteenth-century abolitionism to Black Lives Matter today, progressive social movements have been at the forefront of social change. Yet it is seldom recognized that such movements have not only engaged in political action but also posed crucial philosophical questions about the meaning of justice and about how the demands of justice can be met. Michele Moody-Adams argues that anyone who is concerned with the theory or the practice of justice―or both―must ask what can be learned from social movements. Drawing on a range of compelling examples, she explores what they have shown about the nature of justice as well as what it takes to create space for justice in the world. Moody-Adams considers progressive social movements as wellsprings of moral inquiry and as agents of social change, drawing out key philosophical and practical principles. Social justice demands humane regard for others, combining compassionate concern and robust respect. Successful movements have drawn on the transformative power of imagination, strengthening the motivation to pursue justice and to create the political institutions and social policies that can sustain it by inspiring political hope. Making Space for Justice contends that the insights arising from social movements are critical to bridging the gap between discerning theory and effective practice―and should be transformative for political thought as well as for political activism.
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The Black Book of Forex Trading: A Proven Method to Become a Profitable Trader in Four Months and Reach Your Financial Freedom by Doing it [2015] - Epub + Converted pdf
نویسندگان: خلاصه: The Black Book of Forex Trading: A Proven Method to Become a Profitable Trader in Four Months and Reach Your Financial Freedom by Doing it by Paul Langer (Author)
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