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Cancer Stem Cell Markers and Related Network Pathways - Original PDF
Cancer Stem Cell Markers and Related Network Pathways - Original PDF
نویسندگان: Shihori Tanabe خلاصه: This book entitled “Cancer Stem Cell Markers and Related Network Path-ways” is about cancer stem cell (CSC) markers and the molecular network pathways. CSCs play an important role in the cancer drug resistance, metastasis and recurrence. Epithelial-mesenchymal transition (EMT) is closely related to CSC phenotype. This book covers various aspects of the molecular networks related to CSCs including the important phenotypic change such as EMT. Readers will discover the importance of the identification of CSC markers and EMT-related molecules in CSC network pathways. The CSC signaling pathways and EMT molecular network pathways attract researchers in the field to define the cancer therapeutic targets. Cancer environment is important in the acquisition of CSC phenotype in cells. The revealing of this CSC mystery is across 7 chapters. The topic of this book is particularly relevant to research in the field of cancer and stem cells, as well as the network pathways. We hope that this book helps the readers to be interested in understanding why the CSC concept is important and attractive.
Deep Learning in Cancer Diagnostics: A Feature-based Transfer Learning Evaluation - Original PDF
Deep Learning in Cancer Diagnostics: A Feature-based Transfer Learning Evaluation - Original PDF
نویسندگان: Mohd Hafiz Arzmi, Anwar P. P. Abdul Majeed, Rabiu Muazu Musa, Mohd Azraai Mohd Razman, Hong-Seng Gan, Ismail Mohd Khairuddin, Ahmad Fakhri Ab. Nasir خلاصه: Cancer is the leading cause of mortality in most, if not all, countries around the globe. It is worth noting that the World Health Organisation (WHO) in 2019 estimated that cancer is the primary or secondary leading cause of death in 112 of 183 countries for individuals less than 70 years old, which is alarming. In addition, cancer affects socioeconomic development as well. The diagnostics of cancer are often carried out by medical experts through medical imaging; nevertheless, it is not without misdiagnosis owing to a myriad of reasons. With the advancement of technology and computing power, the use of state-of-the-art computational methods for the accurate diagnosis of cancer is no longer far-fetched. In this brief, the diagnosis of four types of common cancers, i.e., breast, lung, oral and skin, are evaluated with different state-of-the-art feature-based transfer learning models. It is expected that the findings in this book are insightful to various stakeholders in the diagnosis of cancer.
British Tourism, Second Edition: The remarkable story of growth (British Tourism Series) (British Tourism Series) - Original PDF
British Tourism, Second Edition: The remarkable story of growth (British Tourism Series) (British Tourism Series) - Original PDF
نویسندگان: Victor T C Middleton, Leonard J Lickorish خلاصه: Tourism at any point in time is in many ways a mirror of economic and social change. The changes in British society in the decades from the 1950s to the 21st century are reflected in the forms of tourism that the British have been able to aspire to and afford. 'British Tourism: A Remarkable Story of Growth' identifies the most significant of these changes and places them in an historical context highlighting four distinctive eras. Now in paperback it includes four colour photos as well as two brand new chapters on tourism in Scotland and Wales.It looks in detail at the following key areas: * The roots of post war tourism growth * Developments in transport and regulation * Developments in accommodation and visit attractions * Marketing developments and trends - the role of entrepreneurs * Tourism trends into the 21st centuryOffering a comprehensive evaluation of post war developemnts in the British tourism industry, British Tourism: The remarkable story of growth, acts as a single reference resource suitable for a wide ranging readership from students on tourism courses and practitioners in the travel and tourism industries * Now in paperback with colour photos, and two brand new chapters on tourism in Scotland and Wales* Offers comprehensive evaluation of post war developments in the British tourism industry * Acts as a single reference resource for students and academic researchers
Life’s Amazing Secrets: How to Find Balance and Purpose in Your Life - PDF
Life’s Amazing Secrets: How to Find Balance and Purpose in Your Life - PDF
نویسندگان: Das خلاصه: Crawling through the ruthless Mumbai traffic for hours on end, Gaur Gopal Das strikes up a conversation with his friend and young millionaire, Harry. Together, they explore the great frustrations of human condition in Harry's luxury sedan. To most of us, the modern city-life is like a battlefield, throwing up new challenges that leave us feeling stressed and defeated. That corporate job, the competition, financial pressures, strained relationships, rising crime, inflation... we wonder if there will ever be respite? Gaur Gopal Das, the immensely popular life-coach and an ISKCON monk, believes there is a way out and through this book, Life's Amazing Secrets he shows you how to conquer your daily battles, align yourself with your purpose and win at life!
Ikigai : the Japanese secret to a long and happy life - PDF
Ikigai : the Japanese secret to a long and happy life - PDF
نویسندگان: Héctor García خلاصه: According to the Japanese, everyone has an ikigai—a reason for living. And according to the residents of the Japanese village with the world’s longest-living people, finding it is the key to a happier and longer life. Having a strong sense of ikigai—where what you love, what you’re good at, what you can get paid for, and what the world needs all overlap—means that each day is infused with meaning. It’s the reason we get up in the morning. It’s also the reason many Japanese never really retire (in fact there’s no word in Japanese that means retire in the sense it does in English): They remain active and work at what they enjoy, because they’ve found a real purpose in life—the happiness of always being busy.
Advances in Pharma Business Management and Research - Original PDF
Advances in Pharma Business Management and Research - Original PDF
نویسندگان: Lars Schweizer, Theodor Dingermann, Otto Quintus Russe, Christian Jansen خلاصه: Currently, the pharmaceutical industry is facing rapid changes occurring e.g. as a result of biotechnology’s development, the raising importance of IT/Big data as well as new tailor-made gene therapies or the CRISPR/CAS technology. This chapter is based on the observation that the management and science in the pharmaceuticak industry is changing dramatically. The title of this book “Advances in Pharma Business Management and Research, Volume 1” reflects the diversity of the included studies and the goal to include and incorporate the different developments, trends, and challenges in the pharmaceutical industry. Thus, it comprises a number of interesting studies analyzing current challenges in the industry
Shoe Dog: A Memoir by the Creator of NIKE - PDF
Shoe Dog: A Memoir by the Creator of NIKE - PDF
نویسندگان: N.A خلاصه: In 1962, fresh out of business school, Phil Knight borrowed $50 from his father and created a company with a simple mission: import high-quality, low-cost athletic shoes from Japan. Selling the shoes from the boot of his Plymouth, Knight grossed $8000 in his first year. Today, Nike's annual sales top $30 billion. In an age of start-ups, Nike is the ne plus ultra of all start-ups, and the swoosh has become a revolutionary, globe-spanning icon, one of the most ubiquitous and recognisable symbols in the world today.
A Rational Approach to Cancer Treatment - and Why Big Pharma isn't interested - Original PDF
A Rational Approach to Cancer Treatment - and Why Big Pharma isn't interested - Original PDF
نویسندگان: David Bolton خلاصه: While caring for my mother, who had cancer (soft-tissue sarcoma), I began to learn everything I could about the treatments offered by modern medicine, most especially, chemotherapy. I was horrified at the facts I discovered: namely, scientific evidence that for nine types of common cancer, chemo contributes absolutely nothing to five-year survival rates - even though oncologists regularly recommend chemo for those types of the disease! This book represents many months of research, and due to the importance of the subject, I am giving it away for free. It will show you facts that everyone should be aware of, both concerning the abuses of the "Industry", as well as practical guidelines that almost surely will help cancer sufferers, whether or not they opt for a "standard" treatment.
The Hard Thing About Hard Things: Building a Business When There Are No Easy Answers - PDF
The Hard Thing About Hard Things: Building a Business When There Are No Easy Answers - PDF
نویسندگان: Ben Horowitz خلاصه: Ben Horowitz, cofounder of Andreessen Horowitz and one of Silicon Valley's most respected and experienced entrepreneurs, offers essential advice on building and running a startup—practical wisdom for managing the toughest problems business school doesn’t cover, based on his popular ben’s blog. While many people talk about how great it is to start a business, very few are honest about how difficult it is to run one. Ben Horowitz analyzes the problems that confront leaders every day, sharing the insights he’s gained developing, managing, selling, buying, investing in, and supervising technology companies. A lifelong rap fanatic, he amplifies business lessons with lyrics from his favorite songs, telling it straight about everything from firing friends to poaching competitors, cultivating and sustaining a CEO mentality to knowing the right time to cash in. Filled with his trademark humor and straight talk, The Hard Thing About Hard Things is invaluable for veteran entrepreneurs as well as those aspiring to their own new ventures, drawing from Horowitz's personal and often humbling experiences.
Tucker Carlson interviews Dr Aseem Malhotra on the corruption of medicine by Big Pharma - Original PDF
Tucker Carlson interviews Dr Aseem Malhotra on the corruption of medicine by Big Pharma - Original PDF
نویسندگان: Tucker Carlson, Dr Aseem Malhot خلاصه: Dr Aseem Malhotra is a prominent published UK cardiologist that is seen from time to time on the BBC, et al and who is well-connected to British Medical Societies, Academia (including Stanford) and who is an advisor to members of Parliament on a non-partisan basis. He describes himself as a public health advocate who wants the public to have truthful information about health so they can make quality decisions, truth with a capital T. Aseem Malhotra could be called the MLK of British Medicine, a vocal influential advocate for truth and safety in medical practice and public health policy. He is there with an educated smile to face the fire hoses and angry dogs of corporate media attacks. “When you tell the truth, you have to let go of the outcome.” His most recent 10,000 word peer-reviewed paper was instrumental is showing academically that the jabs are WAY more deadly than the disease. In Dec. 2022 he started giving web presentations that reflect what he has been saying in Britain and his journey centers around the story of the recent death of his father via heart failure. Both he and his father have been vaccinated and he works in a vaccination clinic himself. He has an important and touching story to tell. He is a gifted medical writer and thinker about what is happening and why and what we can do about it. Carlson does a stellar interview where he lets the doctor tells his own story with few interruptions. Two bonus add-ons from Great Britain are appended to better appreciate the popularity and quality of Dr. Malhotra's work. 1) A major public talk to NHS employees "Has Big Pharma Hijacked Evidence-Based Medicine" ** 2) A full-text copy of his new article "Curing the pandemic of misinformation on COVID-19 mRNA vaccines through real evidence-based medicine" from the Journal of Insulin Resistance [J. insul. resist. 2022;5(1), a71]

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