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My New Iphone: 52 Simple Projects to Get You Started - PDF
My New Iphone: 52 Simple Projects to Get You Started - PDF
نویسندگان: Wallace Wang خلاصه: This world I'me afraid is going more and more phone mad by the minute, and it just ain't right anymore. Society today is antisocial enough, and just how more antisocial these new obsessions are going to make people, quite frankly is something I don't really want to think about. It doesn't impress me anymore, phones are a big enough problem now, everything in people's lives being interrupted even more, sorry Mr Gates, you're a very clever man, but it's not right, we've got to try and restore some kind of normality, I don't need to say any more do I?
Drug Transporters: Molecular Characterization and Role in Drug Disposition - PDF
Drug Transporters: Molecular Characterization and Role in Drug Disposition - PDF
نویسندگان: Guofeng You, Marilyn E. Morris, Binghe Wang خلاصه: A comprehensive guide to drug transporters that influence the absorption, distribution, and elimination of drugs in the body The development of powerful expression cloning and genome analysis techniques has facilitated the molecular identification and characterization of numerous transporters that play a crucial role in drug disposition. Explaining the principles of drug transport and the associated techniques, Drug Transporters: Molecular Characterization and Role in Drug Disposition: * Provides a comprehensive overview of drug transporters * Includes specific descriptions of transporter families, including substrate and inhibitor specificity, subcellular and tissue localization, mechanisms governing transport, species differences, the clinical implications of these transporters in human physiology and disease, and their role in drug distribution, elimination, and interactions in drug therapy * Describes transporter-mediated drug disposition, a newly emerging field in drug therapy * Gives a comprehensive summary of drug transport across biological membranes * in the liver, brain, kidney, and intestine * Provides balanced coverage of mechanistic aspects and functional outcomes * Features chapters contributed by distinguished scientists in their specialty areas * Provides sufficient detail to enable non-specialists to understand the principles and techniques This authoritative guide is a practical hands-on desk reference for researchers in academia and the pharmaceutical industry and scientists in government agencies. It is also an excellent text for graduate-level courses in the pharmaceutical and pharmacology fields.
Principles of Tissue Engineering Fifth Edition - Original PDF
Principles of Tissue Engineering Fifth Edition - Original PDF
نویسندگان: Robert Lanza, Robert Langer, Joseph Vacanti, Anthony Atala خلاصه: Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production – is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field.
Serotonin und akustisch evozierte Potentiale - PDF
Serotonin und akustisch evozierte Potentiale - PDF
نویسندگان: Georg Juckel خلاصه: Aufgrund dieser Bedeutung des serotonergen Systems konzentrierte sich zunachst die psychopharmakologische Forschung im wachsendem Mane auf die Entwicklung von Substanzen, die moglichst selektiv das serotonerge System beeinflussen (2.B. Selektive Serotonin-Wiederaufnahmehemmer (SSRI)), und auf die Beobachtung der klinischen Response auf diese Pharmaka bei Untergruppen psychiatrischer Patienten (Montgomery und Fineberg, 1989; Feighner und Boyer, 1991). Zudem gelang es der neurobiologischen Forschung, auf der Suche nach der Klarung der pathogenetischen Rolle des serotonergen Systems bei verschiedenen psychiatrischen Erkrankungen wie Depression oder Zwangsstorung, wesentliche Bestandteile und Aspekte seiner Neurotransmission zu ergrunden. lnsgesamt jedoch ist das serotonerge System hinsichtlich seiner Funktion und pathogenetischen Bedeutung aufgrund seiner Komplexitat und nicht zuletzt aufgrund der bisher fehlenden validen lndikatoren fur seinen generelien Funktionszustandes nicht vollstandig verstanden worden und lasst noch viele Fragen offen
Price Action Market Traps: 7 Trap Strategies Market Psychology Minimal Risk & Maximum Profit - Epub + Converted Pdf
Price Action Market Traps: 7 Trap Strategies Market Psychology Minimal Risk & Maximum Profit - Epub + Converted Pdf
نویسندگان: Ray Wang خلاصه: Price Action Market Traps: 7 Trap Strategies Market Psychology Minimal Risk & Maximum Profit by Ray Wang
China’s Food Security - Original PDF
China’s Food Security - Original PDF
نویسندگان: Wang Hongguang خلاصه: Our planet was formed about 4.5 billion years ago, while human beings evolved 2 or 3 million years ago, and the history of growing grain began more than 10,000 years ago. Following the agricultural and indus- trial civilizations, we are currently in the age of information civilization. Humans have landed on the moon, soared freely in space, but yet to get rid of hunger! Human history has witnessed several wars over food and land. Many nations prospered because of food, but many regimes perished because of food shortages. Being a primary human need, food has always been an influential factor for the survival and health of human beings, and a prerequisite for peace and stability of the world. Based on our history and experience, food is essential to human beings, to economic devel- opment, to social stability, and to national autonomy. Food is also a bargaining chip for diplomatic negotiations and a tool for international competition
Understanding gut microbiomes as targets for improving pig gut health (Burleigh Dodds Series in Agricultural Science, 103)[2022] - Original PDF
Understanding gut microbiomes as targets for improving pig gut health (Burleigh Dodds Series in Agricultural Science, 103)[2022] - Original PDF
نویسندگان: Prof. Mick Bailey خلاصه: Understanding gut microbiomes as targets for improving pig gut health (Burleigh Dodds Series in Agricultural Science, 103) by Prof. Mick Bailey (Editor, Contributor), Emeritus Professor Chris Stokes (Editor, Contributor), Dr Laura Peachey (Contributor), Dr Sarah Lambton (Contributor), Dr Weilan Wang (Contributor), Dr Tingting Ju (Contributor), Prof Michael Gänzle (Contributor), Dr James T. Cullen (Contributor), Dr Peadar Lawlor (Contributor), Dr Gillian E. Gardiner (Contributor), Dr Thomas C. A. Hitch (Contributor), Dr David Wylensek (Contributor), Dr Jürgen Harlizius (Contributor), Prof Tom Clavel (Contributor), Dr Chunlong Mu (Contributor), Prof Weiyun Zhu (Contributor), Dr Marion Borey (Contributor), Dr Jordi Estelle (Contributor), Dr Claire Rogel-Gaillard (Contributor), Dr Barbara U. Metzler-Zebeli (Contributor), Dr Barbara A. Williams (Contributor), Dr Michael J. Gidley (Contributor), Dr David Torrallardona (Contributor), Dr Joan Tarradas (Contributor), Dr Núria Tous (Contributor), Charlotte Lauridsen (Contributor), Dr Ole Højberg (Contributor), Dr Nuria Canibe (Contributor), Dr P. Bosi (Contributor), Dr D. Luise (Contributor), Dr P. Trevisi (Contributor), Dr Kim C. M. Lammers-Jannink (Contributor), Dr Stefanía Magnúsdóttir (Contributor), Dr Wilbert F. Pellikaan (Contributor), John R. Pluske (Contributor), Dr Walter J. J. Gerrits (Contributor)
The Political Economy of the China-Pakistan Economic Corridor - Original PDF
The Political Economy of the China-Pakistan Economic Corridor - Original PDF
نویسندگان: Bai Gao • Zhihong Zhen خلاصه: The China-Pakistan Economic Corridor (CPEC) is the pilot project of China’s Belt and Road Initiative (BRI). This is China’s first government- to-government project with an aim to comprehensively promote the eco- nomic development of another country along the Silk Road. As China’s first overseas project with large-scale investment, CPEC has presented both the Chinese government and Chinese companies two major chal- lenges: not only must they undertake an adjustment process to situate themselves within the foreign political, economic, cultural, and religious environments, but they must implement CPEC projects via Pakistani insti- tutions and mechanisms which function under operational logics quite different from those at home. Analyzing the Chinese and Pakistani experi- ences during the early stage of CPEC can provide valuable insights that help us understand the political economy of the BRI
Zufallsbefunde in der Skelettradiologi - Original PDF
Zufallsbefunde in der Skelettradiologi - Original PDF
نویسندگان: Jürgen Freyschmidt خلاصه: Vorwort Die sich in der Radiologie schon längst etablierte und ständig weiter zunehmende Bilderflut sowie die Modalitäten und Erfolge der Krebstherapien mit ausgedehnten prätherapeutischen und langfristigen Nachsorgeuntersuchungen führen zwangsläufig zur Aufdeckung von immer mehr Zufalls- und Nebenbefunden, die vor allem dem Nichtspezialisten in der Skelettradiologie erhebli- che interpretatorische Probleme bereiten können. Doch wie geht man damit um? Sicherlich nicht, indem man die Bilderflut durch mehr oder weniger ungezielte zusätzliche Unter- suchungsverfahren ausweitet und damit unter Umständen neue Zufallsbefunde kreiert. Das gilt besonders für hoch sensitive aber weniger spezifische Modalitäten. Der anspruchsvolle und präzise Radiologe wird vielmehr ein ergänzendes Verfahren einsetzen, das – an der anatomischen Struktur des Zufallsbefunds orientiert – eine höhere Spezifität besitzt und zu einer begründeten und klinisch brauchbaren Diagnose führt. Der häufig angewendete Trick, sich der Verantwortung zu entziehen und eine histologi- sche Abklärung zu empfehlen, sollte gemieden werden. Denn die histologische Interpretation des Pathologen kann in der Skelett- radiologie nur so gut sein, wie der radiologische Befund klar und richtungsweisend ist. Ich betätige mich seit vielen Jahren als Konsiliarius in der Ske- lettradiologie. Das eingesandte Krankengut besteht zu etwa 50 % aus klinisch asymptomatischen Zufallsbefunden, hinter denen benigne Knochentumoren und tumorähnliche Läsionen, Erkran- kungen im Frühstadium, Teile einer systemischen Erkrankung, ungewöhnliche Normvarianten und vieles mehr stecken können. Es wird an mehr als 160 Fällen und fast 100 differenzialdiag- nostisch passenden Kasuistiken aufgezeigt, wie man professionell an solche Befunde unter Einbeziehung der individuellen Situation des Patienten herangeht, welche Relevanz sie haben und welche sinnvollen Empfehlungen man zum weiteren Prozedere geben kann. Mein Dank für die Überlassung der besonderen Fälle gilt den Kollegen CA Dr. med. Jürgen Wiens, Wolfsburg (Fall 22), Dr. med. Thomas Grieser, Augsburg (Fall 30), Professor Dr. med. Michael Laniado, Dresden (Fälle 34, 61), Privt.-Doz. Dr. Sönke Langner, Greifswald (Fall 45) und CA Dr. med. Nils H. Goecke, Wildes- hausen (Fall 131).
NONVIOLENCE AND EDUCATION Cross-Cultural Pathways - Original PDF
NONVIOLENCE AND EDUCATION Cross-Cultural Pathways - Original PDF
نویسندگان: Hongyu Wang خلاصه: This book is based on a life history, qualitative study of four university professors’ cross-cultural pathways. When I started this research during my sabbatical leave in China in September, 2009, I had no idea what it would lead me to. To my aston- ishment, it turned out to be one of the most spiritual experiences in my life. As a result, I became fully committed to nonviolence education, inspired by the life stories of the four professors in their cross-cultural engagements situated in history, culture, and educational contexts. Two Chinese professors, one male and one female, and two American pro- fessors, one male and one female, from different generations participated in this study. This book tells these professors’ extraordinary stories of encountering a culture different from their own and how such engagements influenced their edu- cational work. Specifically, the Chinese professors’ engagement with American/ Western thought and culture and the American professors’ engagement with Chi- nese thought and culture are narrated. Their stories are also situated in the context of the intellectual and cultural history of China–US engagement, with my auto- biographical voice woven in when applicable. While Chinese immigrants’ stories are more often heard in the North American educational field, Americans’ lived experiences in China must also be heard to achieve the mutuality that is necessary for forming constructive relationships between the self and the other globally (Aoki, 2005). It is at the site of mutuality that non-dualistic engagement with dif- ference becomes possible in cross-cultural and intercultural education. Nonviolence has emerged as a central thread of cross-cultural pathways and pedagogy. Here nonviolence is defined as unity between the body and the mind within the self and compassionate relationships between the self and the other that can be extended to the group, the nation, and the global (and further to the ecological relationship between humanity and nonhuman being

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