موضوعات
آموزش و پرورش
ادبیات و زبان
پزشکی، دندانپزشکی و داروسازی
تاریخ و جغرافیا
داستان و رمان
دیگر
دین و فلسفه
روانشناسی
ریاضیات و آمار
سلامتی، تناسب اندام و رژیم غذایی
شیمی و پلیمر
علوم اجتماعی و حقوق
علوم زیستی و بیوتکنولوژی
فیزیک و نجوم
کامپیوتر و اینترنت
کتابهای کودکان و داستان
کسب و کار و اقتصاد
کشاورزی و دامپزشکی و غذا
معماری
مهندسی و فناوری
هنر و تئاتر
محصولات
Veterinary Immunology 10E - Original PDF
نویسندگان: خلاصه: This textbook was first published in 1977, at a time when veterinary immunology was relatively new and poorly understood. Nevertheless, it was recognized, even then, that immunology held the key to many of the significant issues in veterinary medicine. The importance of immunology has not declined since then, except among those tasked with establishing college curricula. The decline in basic science instruction at colleges of veterinary medicine in favor of more clinical training has resulted in graduating a generation of veterinarians whose knowledge of immunology is minimal. Yet immunology continues to be a key science. It is central to our understanding of major veterinary issues such as vaccination, cancer, infectious diseases, and allergies. It has been tempting to dilute the contents of this text and its associated website to conform to current curricular trends. I have resisted this. Because the amount of knowledge of immunology required to obtain a veterinary degree has been progressively reduced, the need to document the science in depth has correspondingly increased. This book therefore continues to grow as the result of opening up new, exciting areas of the science. Veterinarians need to know much of this if they are to practice cutting-edge science in the 21st century. Read it, study it, and enjoy its wonderful complexity. Over the many years that this textbook has been published we have seen many changes in the science of immunology. In most cases, these changes have been gradual in nature as investigators add detail to existing knowledge. Occasionally, however, major leaps are made that effectively revolutionize the discipline—socalled paradigm shifts. For example, in the late 1990s, the concept of innate immunity was accepted. Inflammation and other processes were finally recognized as being essential components of the immune system and the dual innate and adaptive immune systems were shown to complement each other. It is interesting to note that this was not a new discovery but a new way of looking at well recognized processes. This new edition also reflects revolutionary changes in the way we think of immunology. Like the concept of innate immunity, these changes are not a result of a previously unknown process but a belated recognition of something known about since the dawn of microbiology, the body's normal microbiota. New methodologies and intensive studies have revealed that many body processes, especially immunity, are regulated by the diverse microbiota that colonizes all body surfaces. Much of immunology has had to be reassessed in the light of this new knowledge. Both innate and adaptive immunity are regulated by those organisms, especially bacteria, that live in the intestine and respiratory tract and on the skin. Many previously unexplained phenomena have now been shown to depend on the normal microbiota. As a result of this new information, the reader will encounter the microbiota at every turn in this book, plus a completely new chapter on the subject. The second new chapter deals with allergic diseases. For many years, these were readily explained by the production of IgE against allergens. The most recent information, however, has demonstrated that allergies are much more complex than this. For example, atopic dermatitis, one of the most common conditions seen by small animal veterinarians, is likely a syndrome with multiple complex causative factors. As a result, allergic and inflammatory diseases deserve a new chapter. These additions cannot, however, hide the fact that the rest of immunology also continues to move forward. Thus the mechanisms by which the body rejects gastrointestinal helminths has been clarified with the discovery of the importance of tuft cells and interleukin-33. Associated with this has been the recognition of the complex nature of innate lymphoid cells and their subpopulations. Some of these advances can be considered routine, such as the identification of new cell surface molecules and many new cytokines. New disease syndromes such as swine SCID, bovine neonatal pancytopenia, and immune-mediated keratoconjunctivitis are now described, and the pathogenesis of others such as atopic dermatitis, type I diabetes mellitus, equine laminitis, and systemic lupus are shown to be more complex than previously believed. New advances in therapy are covered, including the introduction of immune checkpoint therapy in cancer and the use of monoclonal antibody therapy and intravenous immunoglobulin therapy for immune-mediated diseases. The exciting new developments in the use of nanoparticles in vaccines and as adjuvants are now described. The significant roles of vitamins A and D as well as the aryl hydrocarbon receptor in immunity are also recognized. Advances in basic science that are now discussed include new findings on the structure and genetics of bovine antibodies, epigenetics, RNA interference, microRNA, macrophage polarization, and type 1 and type 2 immune responses. I make no apologies for the size and complexity of this text. Immunology is a complex subject that has a direct bearing on many of the most important areas of veterinary medicine. Students, as well as graduate veterinarians, ignore it at their peril. Finally, readers are strongly encouraged to visit the Evolve website for this text. The site is also constantly evolving and improving. In it you will be able to find a collection of more than 450 multiple-choice questions (with the answers!) keyed to each chapter; a set of flashcards also linked to chapters; all the text figures available as PowerPoint slides; and a collection of animations kindly provided by Dr. Abul Abbas, as well as brand new animations created for this textbook, designed to clarify some complex processes and pathways where still figures are inadequate. All the chapter references are keyed to PubMed. There are also new hand-outs that students can print off and use as a reference, should you wish. It is my hope that these assets will help you remain current in this rapidly expanding and exciting field.
Principles of Tissue Engineering Fifth Edition - Original PDF
نویسندگان: خلاصه: Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production – is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field.![Saunders Review of Dental Hygiene (2nd Edition) [2008] - Original PDF](https://dl.libsan.ir/images/1/12/1_648030175dedd.jpg)
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We are proud boys - Epub + Converted PDF
نویسندگان: خلاصه: It was late in March 2016, in the heat of Trump’s presidential push, and the national media had latched onto one bit of security footage from a Trump event. The video showed Trump’s campaign manager, Corey Lewandowski, grabbing and pushing Breitbart writer Michelle Fields as she approached Trump and tapped his elbow. Fields claimed that Lewandowski left bruises on her arm. It was enough that police charged Lewandowski with simple battery, but prosecutors ultimately dropped the case. He shrugged off the allegation and the news cycle that followed, which left the pundits to bicker among themselves over the footage and decide whether an assault had occurred. McInnes, staring slack-jawed at the footage during an episode of his reactionary talk show, couldn’t believe it warranted media attention in the first place. A woman touched a presidential candidate and got what was coming to her, he argued. If anything, she deserved more. “She wasn’t randomly grabbed!” he groused, his voice pitching upward in aggravation as the video played. “I think there’s not enough violence in today’s day and age.” McInnes then launched into one of his signature rants, steering the conversation toward his keynote: America had gone soft in the waning years of Barack Obama’s presidency, and there was no better evidence than the news media clutching its pearls over a woman being grabbed and pushed out of the way. Real Americans—real men—wouldn’t give this story the time of day. Real men are hardened by a lifetime of violence
Safety-Critical Automotive Systems - PDF
نویسندگان: خلاصه: Preface The subject of safety-critical automotive systems is growing in importance, as one can see by perusing the latest publications of SAE International. Safety has become an integral and essential part behind the engineering process for the modern vehicle. Vehicle safety is a wide-ranging discipline covering many engineering activities spanning materials, ergonomics, environmental, functional, and so forth. This book covers functional safety, also referred to as system safety. Functional (or system) safety refers to aspects of the overall safety of a vehicle that rely on the vehicle sub-systems producing correct outputs or operating correctly in response to stimuli. The most important vehicle sub-systems are the following: 1. Sensors 2. Actuators 3. Electronic control units (ECUs) 4. Communication systems 5. Software (e.g., application, middleware, drivers) Thus, it is timely that a book covering the most important aspects of functional (i.e., system) safety-critical automotive systems is published. The goals of this book are threefold: 1. To provide a quick introduction to and summary of the subject 2. To provide a classification and analysis of the recent literature on the subject 3. To reproduce the most representative of SAE publications on the subject The task of assembling a book on safety-critical automotive systems is challenging because the subject is complex, involving several technical areas that have contributed to the existing body of knowledge. In addition, the subject is by no means mature. There will be many excellent contributions and publications in the years to come. There are also many good publications in a number of worldwide conferences and/or journals. However, the intent of this book was to consider only SAE publications. Nevertheless, many of the SAE papers in this book include references to other publications. After selecting a number of papers, the question arose as to what criteria should be used to classify these papers. One possible criterion was to organize the papers around the constituent elements of a system (e.g., sensors, actuators, ECUs, communication system, software). Another criterion was to organize the papers along the steps to be followed while building a complete final system. We have decided to use the second criterion. Accordingly, the papers are organized in the following sections: 1. Introduction to safety-critical automotive systems 2. Safety processes to be followed 3. Requirements to be met 4. Analysis and design methods and techniques 5. Prototyping and target implementation 6. Testing, verification, and validation meth
OET Veterinary Science_ Official OET Practice Book - Original PDF
نویسندگان: خلاصه: OET is an international English language test that assesses the language proficiency of healthcare professionals seeking to register and practise in an English-speaking environment. It provides a validated, reliable assessment of all four language skills – listening, reading, writing and speaking – with the emphasis on communication in healthcare professional settings. OET tests candidates from the following 12 health professions: Dentistry, Dietetics, Medicine, Nursing, Occupational Therapy, Optometry, Pharmacy, Physiotherapy, Podiatry, Radiography, Speech Pathology and Veterinary Science. Candidates are encouraged to prepare thoroughly for their OET test. Language proficiency and test taking skills For more information about OET including the latest test dates and a complete list of test locations and preparation providers, as well as access to our free test preparation package Start for Success, visit the OET website: www.occupationalenglishtest.org About the test OET assesses listening, reading, writing and speaking. There is a separate sub-test for each skill area. The Listening and Reading sub-tests are designed to assess the ability to understand spoken and written English in contexts related to general health and medicine. The sub-tests for Listening and Reading are common to all professions. The Writing and Speaking sub-tests are specific to each profession and are designed to assess the ability to use English appropriately in the relevant professional context
OET Optometry_ Official OET Practice Book 1_ For tests from 31 August 2019_nodrm - PDF
نویسندگان: خلاصه: OET is an international English language test that assesses the language proficiency of healthcare professionals seeking to register and practise in an English-speaking environment. It provides a validated, reliable assessment of all four language skills – listening, reading, writing and speaking – with the emphasis on communication in healthcare professional settings. OET tests candidates from the following 12 health professions: Dentistry, Dietetics, Medicine, Nursing, Occupational Therapy, Optometry, Pharmacy, Physiotherapy, Podiatry, Radiography, Speech Pathology and Veterinary Science. Candidates are encouraged to prepare thoroughly for their OET test. Language proficiency and test taking skills For more information about OET including the latest test dates and a complete list of test locations and preparation providers, as well as access to our free test preparation package Start for Success, visit the OET website: www.occupationalenglishtest.org About the test OET assesses listening, reading, writing and speaking. There is a separate sub-test for each skill area. The Listening and Reading sub-tests are designed to assess the ability to understand spoken and written English in contexts related to general health and medicine. The sub-tests for Listening and Reading are common to all professions. The Writing and Speaking sub-tests are specific to each profession and are designed to assess the ability to use English appropriately in the relevant professional c
TALENT DEVELOPMENT IN PARALYMPIC SPORT: RESEARCHER AND PRACTITIONER PERSPECTIVES - Original PDF
نویسندگان: خلاصه: dentifying and developing talented athletes to their fullest potential is a central concern of coaches, sports scientists, and sports policymakers. However, there is currently limited practical and theoretical knowledge for those working in Paralympic sport. A systematic review by our research team (Dehghansai et al., 2017a), for example, highlighted the clear lack of literature examining athlete development. Subsequent studies (Dehghansai et al., 2017b; Dehghansai & Baker, 2020; Dehghansai et al., 2020, 2022, 2021, Houlihan & Chapman, 2017; Patatas et al., 2020, 2022) from research groups around the world have expanded our understanding, and provided the impetus for this book, which aims to synthesize the most up-to-date research with practice across international Paralympic sport systems (e.g., from those in Australia, Belgium, Brazil, Canada, Czech Republic, United Kingdom, United States, Netherlands, and New Zealand). As part of Australia’s preparation for the Tokyo 2020 Paralympic Games, two of the authors/editors have experienced first-hand the potential opportunities for supporting athlete development. We have witnessed rapid performance trajectories, the quality and passion of coaches and other practitioners working in this field, and the creativity required to solve problems. We also observed (and experienced) many of the challenges that are highlighted and discussed at length throughout this book. We worked closely with sports which, during this period (i.e., 2016–2021), resulted in athletes winning medals at the 2020 Paralympic Games who were not even participating in that sport during the time of the previous Paralympic Games (i.e., Rio 2016 Paralympic Gamesآیا کتاب مورد نظر هنوز بر روی سایت قرار نگرفته است؟ جای نگرانی نیست! کافی است بر روی گزینه سفارش کتاب کلیک کرده و درخواست خود را ثبت کنید. در کمتر از چند ساعت کتاب شما را آماده خواهیم کرد.