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Visceral Pain - Original PDF
Visceral Pain - Original PDF
نویسندگان: Stuart M. Brierley, Nick J. Spencer خلاصه: Presents the latest research on visceral pain Features contributions from preeminent researchers in the fields of the enteric nervous system and visceral pain Covers hot topics such as the microbiome and gut-brain axis, and optogenetic probing of nociceptive pathways
Drug Development in Psychiatry - Original PDF
Drug Development in Psychiatry - Original PDF
نویسندگان: Matthew Macaluso, Sheldon H. Preskorn, Richard C. Shelton خلاصه: Reviews critical elements of both basic and clinical science as they pertain to drug development in psychiatry It covers both historical elements and modern interpretations to understand best practices in drug development It appeals to both beginning and mature researchers as well as clinicians
Advances in Maternal-Fetal Biomedicine - Original PDF
Advances in Maternal-Fetal Biomedicine - Original PDF
نویسندگان: Marcelo Gonzalez-Ortiz خلاصه: Contains molecular descriptions of relevant pathologies of pregnancy Written by a leading group of researchers who are at the frontier of knowledge in maternal-fetal biomedicine Offers an integrative view that includes clinical information and translational medicine approaches
Desert Malaria - Original PDF
Desert Malaria - Original PDF
نویسندگان: B.K. Tyagi خلاصه: Covers epidemiology, diagnosis, and disease dynamics of desert malaria Discusses response of malaria epidemics to climate forcing Reviews strategies for the control and management of desert malaria
Cognitive Aging and Brain Health - Original PDF
Cognitive Aging and Brain Health - Original PDF
نویسندگان: Zhanjun Zhang خلاصه: Including neurophysiological mechanisms, clinical research and intervention measures of cognitive aging Providing with the latest research findings and in-depth opinions of the cognitive aging and brain health Assisting researchers to grasp the theories, practice and trends of cognitive aging
Libraries, the First Amendment, and Cyberspace: What You Need to Know - PDF
Libraries, the First Amendment, and Cyberspace: What You Need to Know - PDF
نویسندگان: Robert S. Peck خلاصه: Too often misinformation about free speech is circulated as if it wereauthoritative. The final straw for me and the inspiration for thisbook was a panel discussion at a state library association convention.There, as a member of the audience, I was treated to a confidently ren-dered but distorted description of First Amendment law as it applies topublic libraries. As a legal matter, the speaker said, obscenity is some-thing you know when you see it. This was decidedly wrong as a state-ment of the law, and I was unable to await my own scheduled talk laterthat day. I stood up during the question period and explained what theU.S. Supreme Court had actually said about obscenity and how theConstitution requires substantial procedural safeguards to be followedbefore a librarian may adjudge material obscene and take the matter tocourt. In defense, the panelist, a nonlawyer, justified her statements asbased on what her city attorney had told her.Of course, few city attorneys have much experience with FirstAmendment law. Their loyalties may not run to civil liberties as much asto whatever powers hold sway locally. In such instances, libraries arestuck with advice that has a more political than legal basis. For toomany who provide that advice, the need to avoid controversy over-whelms fidelity to the law. Such political considerations, however,should not be part of the constitutional calculus—for the reasons toknuckle under to would-be censors are infinite and can only expandwith each new concession. The result of such a standard operating pro-cedure would then be an abandonment of the library’s very purpose andmission: to assist in the diffusion of knowledge.vI N T R O D U C T I O NNeither ignorance of the law nor frustration over its complexity oughtto deter compliance with the principles it sets out. Even though the law isfilled with subtle touchstones, guidelines, and three-part tests that courtshave difficulty applying, there are some basic and unimpeachable tenetsthat all can understand and act upon. Librarians and library policymak-ers, dedicated as they are to providing access to information, need an ac-curate basis upon which to base intelligent and legally appropriatepolicies about Internet access, as well as the other issues that librariesoften face. This book aims to provide that foundation.The development of constitutionally informed policies can ease someof the conflict that is bound to arise. To be sure, it will not end that con-flict because speech, the written word, and pictures have an unquench-able capacity to generate controversy. It is almost a guarantee thatwhatever policies are eventually adopted will still be matters of greatcontention, activating factions who object to the materials thus madeavailable or unavailable to the community. It is indisputable that li-braries have become the front lines in modern free-speech wars. Still, awell-conceived policy can absorb some of the pain that accompaniesthat unfortunate reality and make all the difference in the litigation thatmay well follow.The role of libraries at the center in the battle over the nation’s intel-lectual freedoms is a familiar and long-running one. Almost from themoment of inception for public libraries, vociferous debates have en-sued about material that someone or another has deemed inappropriatefor shelving. One of the most enduring controversies over a book in theUnited States has been over Mark Twain’s Adventures of HuckleberryFinn. As far back as 1885, the Concord, Massachusetts, Public Librarybanished the now-classic book as “the veriest trash” and “more suitedto the slums than to intelligent, respectable people.” 1 The book remainsenormously controversial to this day.As recently as October 19, 1998, the U.S. Court of Appeals for theNinth Circuit was forced to rule on yet another attempt to remove thatbook—this time from a mandatory high-school freshman reading list inTempe, Arizona. The court concluded that assignment of the book didnot violate the constitutional right to equal protection of the laws, norcould it be removed because it allegedly contributed to a racially hostilelearning environment.2 Huckleberry Finn has endured more than a cen-tury of controversy with no sign that the hackles it raises will abate.Cyberspace now poses additional challenges for libraries.
The Body Sense Natural Diet: Six Weeks to a Slimmer, Healthier You - Original PDF
The Body Sense Natural Diet: Six Weeks to a Slimmer, Healthier You - Original PDF
نویسندگان: : Lorna R. Vanderhaeghe خلاصه: I never worry about diets. The only carrots that interestme are the number you get in a diamond.”— Mae West —Mae West may have been on to something when it comes to diets. Thesad fact is that most diets don’t work because they fail to look at theunderlying cause of weight gain and only focus on caloric intake, carbo-hydrate or protein consumption, and increased exercise. All these factorsare important, but all you dieters who have run thousands of miles on thetreadmill and eaten buckets of carrot sticks must know by now that thereis more to weight loss than just eating low-calorie foods, exercising, andusing a lot of willpower.During the research for The Body Sense Natural Diet, I read every dietbook currently in print and thousands of research papers. Most diet booksprovide good advice that, if followed long-term, would help you lose someweight. But the sad story is that most dieters gain back one- to two-thirdsof the weight they lost by the end of the first year, and almost all theweight will be gained back (and more!) within five years. The question iswhy. Stress, emotions, aging, and other factors play a role.1IntroductionI n t r o d u c t i o n2The key to permanent weight loss is well hidden. It lies in understand-ing how each component of dieting affects the hormones that stimulate,regulate, and control thousands of functions in your body. Those hormonesconspire to make your fat cells bigger, increase your cravings, tell you to eatmore, lower your fat-burning rate, and disrupt your blood sugar. None of thediet books I read explain this or integrate the knowledge into their advice,and yet there are mountains of research on the hormones of obesity.Within the pages of this book you will find the latest scientific break-throughs in fat loss—including which hormones are conspiring to makeyou fat. By using foods, nutrients, and other factors, you can correct hor-monal imbalances and reset your body’s fat-burning furnace, makingweight loss much easier.The Body Sense Natural Diet is a simple guide that takes you throughthe hormonal maze and unlocks secrets to diet success. You must normal-ize key hormones to lose weight and keep it off. Once you understand howfoods and lifestyle factors affect your hormones and make you fat or thin,you will recognize why other diets don’t work.Why am I sure it’s hormones? Think about it. Menopausal womenhave been telling their doctors for decades that the hormonal change theyexperience during this time of transition leads to weight gain that is verydifficult to shed. Women taking hormone replacement therapy, includingestrogen and progestin, also notice large weight gains and are unable tolose that weight. Research has proven that low thyroid slows your meta-bolic rate and causes you to gain weight and resist weight loss.Carbohydrate cravings are directly linked to the hormone serotonin, yourfeel-good hormone. When serotonin is low, your body desires sweet,starchy foods to bring serotonin back to desired levels; nothing will stopyou from eating the wrong foods as you satisfy your body’s need for thishormone. Cortisol, your stress hormone, is directly linked to making fatcells resistant to fat loss.Poor digestive-tract health is also linked to weight gain. Poor digestion,candida yeast, and bacteria overgrowth cause the secretion of hormonesthat expand your pants size. Fat cells themselves are hormone factories:the more fat cells you have, and the bigger they are, the more trouble youwill have losing weight. The research is clear—hormones are key to losingthose unwanted pounds and keeping them off for good.
Master Critical Reading for the SAT: What You Need for Test Success, 2nd Edition - PDF
Master Critical Reading for the SAT: What You Need for Test Success, 2nd Edition - PDF
نویسندگان: Peterson's خلاصه: Master Critical Reading for the SAT prepares students for the critical reading test with a detailed review of sentence completions and reading comprehension that are tested on the exam, as well as expert test-taking strategies in an easy-to-use workbook format. Students demonstrate their knowledge with practice questions at the end of each review chapter and full-length practice tests. Unique "Take It to the Next Level" section offers further review and guidance for those who want to score even higher.
Visual Basic .NET! I Didn't Know You Could Do That... - PDF
Visual Basic .NET! I Didn't Know You Could Do That... - PDF
نویسندگان: Matt Tagliaferri خلاصه: Discover Visual Basic .NETVisual Basic .NET! I Didn't Know You Could Do That. . . will help you conquer the .NET learning curve quickly as you make the transition to Microsoft's new programming paradigm. Inside you'll find loads of ideas and advice that will teach you the essential aspects of VB.NET. You'll also find a companion CD loaded with more than 60 ready-to-run pieces of code that you can implement in your VB.NET projects.Stop Monkeyin' Around and Get Up to Speed on VB.NETThis book covers all the key changes in the new version of Visual Basic. Numerous example projects provide both an excellent teaching aid and a great source library. With the tips and tricks in Visual Basic .NET! I Didn't Know You Could Do That..., you'll be impressing your fellow VB programmers in no time.Go Bananas—Become a VB.NET ExpertInside you'll learn how to:Write smarter codeUse new object-oriented language featuresUnderstand garbage collectionUse databasesUse VB objects in ASP.NET pagesWrite and Consume XML web servicesAnd much more!
If You Build It Will They Come: Three Steps to Test and Validate Any Market Opportunity - PDF
If You Build It Will They Come: Three Steps to Test and Validate Any Market Opportunity - PDF
نویسندگان: Rob Adams خلاصه: Know if you'll hit your targets before pulling the trigger on any marketing planMore than sixty five percent of new products are commercial failures, and if you compound this with a recession, now more than ever you can't afford to be wrong. In If You Build It Will They Come, business professor and strategy consultant Rob Adams shows you how to make sure you hit your target market before you spend a lot of money. He shows you the fast, systematic and proven approach of performing Market Validation in advance of making a large product investment.Adams outlines a simple and effective market validation and testing strategy that is proven, giving entrepreneurs and managers the ability to dramatically improve the prospect of product success. He explains how to quickly gather information on competitors, directly interview members of your target market, and figure out what the market really wants to buy, versus what customers say they want. The steps to quickly understanding the viability of your marketWhere to go to gather the information needed to hit the market requirementsHow to follow through with the right product launched in the right wayAdams cuts through the fancy terms and expensive market research that gives lots of data but no real product oriented information about usage, pricing, features and competitive forces. In the end you'll produce results on your first release of a far more mature product, shipped in a faster timeframe with features customers will actually use. This book is for anyone involved with designing, developing and launching new products. Its examples and advice cover everything from the fledgling start-up that needs their first product to work just to survive to the successful Fortune Class company establishing new worldwide markets. Examples cut across all major industrial sectors including consumer, retail, manufacturing, technology, life sciences and services. This book offers the step-based guidance you need to make sure failure is not an option.

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