موضوعات
آموزش و پرورش
ادبیات و زبان
پزشکی، دندانپزشکی و داروسازی
تاریخ و جغرافیا
داستان و رمان
دیگر
دین و فلسفه
روانشناسی
ریاضیات و آمار
سلامتی، تناسب اندام و رژیم غذایی
شیمی و پلیمر
علوم اجتماعی و حقوق
علوم زیستی و بیوتکنولوژی
فیزیک و نجوم
کامپیوتر و اینترنت
کتابهای کودکان و داستان
کسب و کار و اقتصاد
کشاورزی و دامپزشکی و غذا
معماری
مهندسی و فناوری
هنر و تئاتر
محصولات
Veterinary Immunology 10E - Original PDF
نویسندگان: خلاصه: This textbook was first published in 1977, at a time when veterinary immunology was relatively new and poorly understood. Nevertheless, it was recognized, even then, that immunology held the key to many of the significant issues in veterinary medicine. The importance of immunology has not declined since then, except among those tasked with establishing college curricula. The decline in basic science instruction at colleges of veterinary medicine in favor of more clinical training has resulted in graduating a generation of veterinarians whose knowledge of immunology is minimal. Yet immunology continues to be a key science. It is central to our understanding of major veterinary issues such as vaccination, cancer, infectious diseases, and allergies. It has been tempting to dilute the contents of this text and its associated website to conform to current curricular trends. I have resisted this. Because the amount of knowledge of immunology required to obtain a veterinary degree has been progressively reduced, the need to document the science in depth has correspondingly increased. This book therefore continues to grow as the result of opening up new, exciting areas of the science. Veterinarians need to know much of this if they are to practice cutting-edge science in the 21st century. Read it, study it, and enjoy its wonderful complexity. Over the many years that this textbook has been published we have seen many changes in the science of immunology. In most cases, these changes have been gradual in nature as investigators add detail to existing knowledge. Occasionally, however, major leaps are made that effectively revolutionize the discipline—socalled paradigm shifts. For example, in the late 1990s, the concept of innate immunity was accepted. Inflammation and other processes were finally recognized as being essential components of the immune system and the dual innate and adaptive immune systems were shown to complement each other. It is interesting to note that this was not a new discovery but a new way of looking at well recognized processes. This new edition also reflects revolutionary changes in the way we think of immunology. Like the concept of innate immunity, these changes are not a result of a previously unknown process but a belated recognition of something known about since the dawn of microbiology, the body's normal microbiota. New methodologies and intensive studies have revealed that many body processes, especially immunity, are regulated by the diverse microbiota that colonizes all body surfaces. Much of immunology has had to be reassessed in the light of this new knowledge. Both innate and adaptive immunity are regulated by those organisms, especially bacteria, that live in the intestine and respiratory tract and on the skin. Many previously unexplained phenomena have now been shown to depend on the normal microbiota. As a result of this new information, the reader will encounter the microbiota at every turn in this book, plus a completely new chapter on the subject. The second new chapter deals with allergic diseases. For many years, these were readily explained by the production of IgE against allergens. The most recent information, however, has demonstrated that allergies are much more complex than this. For example, atopic dermatitis, one of the most common conditions seen by small animal veterinarians, is likely a syndrome with multiple complex causative factors. As a result, allergic and inflammatory diseases deserve a new chapter. These additions cannot, however, hide the fact that the rest of immunology also continues to move forward. Thus the mechanisms by which the body rejects gastrointestinal helminths has been clarified with the discovery of the importance of tuft cells and interleukin-33. Associated with this has been the recognition of the complex nature of innate lymphoid cells and their subpopulations. Some of these advances can be considered routine, such as the identification of new cell surface molecules and many new cytokines. New disease syndromes such as swine SCID, bovine neonatal pancytopenia, and immune-mediated keratoconjunctivitis are now described, and the pathogenesis of others such as atopic dermatitis, type I diabetes mellitus, equine laminitis, and systemic lupus are shown to be more complex than previously believed. New advances in therapy are covered, including the introduction of immune checkpoint therapy in cancer and the use of monoclonal antibody therapy and intravenous immunoglobulin therapy for immune-mediated diseases. The exciting new developments in the use of nanoparticles in vaccines and as adjuvants are now described. The significant roles of vitamins A and D as well as the aryl hydrocarbon receptor in immunity are also recognized. Advances in basic science that are now discussed include new findings on the structure and genetics of bovine antibodies, epigenetics, RNA interference, microRNA, macrophage polarization, and type 1 and type 2 immune responses. I make no apologies for the size and complexity of this text. Immunology is a complex subject that has a direct bearing on many of the most important areas of veterinary medicine. Students, as well as graduate veterinarians, ignore it at their peril. Finally, readers are strongly encouraged to visit the Evolve website for this text. The site is also constantly evolving and improving. In it you will be able to find a collection of more than 450 multiple-choice questions (with the answers!) keyed to each chapter; a set of flashcards also linked to chapters; all the text figures available as PowerPoint slides; and a collection of animations kindly provided by Dr. Abul Abbas, as well as brand new animations created for this textbook, designed to clarify some complex processes and pathways where still figures are inadequate. All the chapter references are keyed to PubMed. There are also new hand-outs that students can print off and use as a reference, should you wish. It is my hope that these assets will help you remain current in this rapidly expanding and exciting field.
Principles of Tissue Engineering Fifth Edition - Original PDF
نویسندگان: خلاصه: Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production – is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field.
Economics for Business - PDF
نویسندگان: خلاصه: The economic policy consensus has evolved not because the principles of economics have changed, but because over time we have learned more about the inferences that can be drawn from them. Accompanying this consensus are policy priorities, which are having a major impact on global standards of living, income distribution and lifestyles. The global reach of the economic consensus is its most remarkable characteristic. In Europe and North America, the key turning points were the policy reforms of Prime Minister Thatcher and President Reagan in the first half of the 1980s. New Zealand and Australia developed even more radical pro-market policies. In South America, dramatic policy initiatives were taken in Chile during the 1980s, and Chile’s example was followed by Bolivia, Mexico, Colombia, Argentina and Brazil. In Asia, India embraced a reform package in the early 1990s which focused on a more intensive use of market incentives in domestic labour and product markets, openness to trade and foreign investment, and fiscal stability. China too has become more conscious of the need to use market mechanisms. Throughout Eastern Europe and the former Soviet Union, policy-makers have turned away from economic planning and price controls, and are searching for ways of making their markets function more efficiently, through privatisation programmes, market flexibility measures, competition policy and more enterprise-friendly tax regimes
China: The Great Transition From Agrarian Economy to Technological Powerhouse - Original PDF
نویسندگان: خلاصه: The great transition of China from a subsistence agrarian economy to a technolog- ically driven economic powerhouse reflects the achievements of the hardworking Chinese people. China continues to grow as the second largest economy of the world from 2010 onwards. It is going to be the largest economy in the world by putting US economy behind. The Chinese GDP has increased of 1,500 times from 1952. The transformation of China and its economic growth is neither miraculous nor a product of market economy. The economic development in China is a product of political pursuit shaped by the Chinese people led by the Communist Party of China from 1921 onwards. China is not only the workshop of the world today but also works as the engine of global economic growth. The state led development in China paves the path of recovery and provides direction to the crisis ridden global economy. The rapid transition of Chinese economy and its society is profoundly affecting the competitive capabilities of the capitalist economies. There are consistent attempts by the liberal and western intellectuals, commentators and writers to undermine the Chinese politics and achievements of working people of China. The ideologically driven propaganda is a dangerous trap that hides viable alternatives from people. The phenomenal Chinese economic growth and development led to the significant fall of poverty in China. The World Bank (2022) study on “Four Decades of Poverty Reduction in China Drivers, Insights for the World, and the Way Ahead” shows that China lifted 800 million people out of poverty and contributed to three-quarters of the global reduction of extreme poverty. There were 250 million poor living in rural China in 1978 which has declined in a massive scale. There were more than 750 million (about two-thirds of the population) in China lived below international poverty line in 1990. The commitment and targeted approach of the Chinese government has led to the eradication of absolute poverty in China. There is remarkable growth of access an
Research on China’s Monetary Policy System and Conduction Mechanism - Original PDF
نویسندگان: خلاصه: At the initial stages of reform and opening up, Deng Xiaoping put forward the idea of “quadrupling” the national economic aggregate to realize a Chinese-style modernization. Later, he further developed this idea into a “three-step” strategic idea. On April 30, 1987, when meeting with guests from Spain, Deng Xiaoping said, “Our goal for the first step is to reach, by 1990, a per capita GNP of US$500, that is, double the 1980 figure of US$250. The goal for the second step is, by the turn of the century, to reach a per capita GNP of US$1,000. When we reach that goal, China will have shaken off poverty and achieved comparative prosperity. The goal we have set for the third step is the most important one: quadrupling the US$1 trillion figure of the year 2000 within another 30 to 50 years. That will mean a per capita GNP of roughly $4,000 —in other words, a medium standard of living
Study on China’s Industrial Competitiveness - Original PDF
نویسندگان: خلاصه: International competitiveness, which rose in the 1980s and became a hot spot in the world in the 1990s, driven by the economic globalization, information technology revolution and the rapid development of high-tech industry, has gradually become an important research field and attracted the attention of all countries in the world. Economic competition, in the final analysis, is industrial competition. The overall economic competitiveness of a country or region is determined by the competitive- ness of its main industries. With the rapid development of economic globalization and the promise of China to accede to WTO, how to deal with the open international market become the concerned issue of corporate, industrial, government, research institution and the public. China has strong competitiveness in the market potential and human resource. But from 1994 to 2006, the international competitiveness of China was ranked in around 28th dues to the weakness of enterprise competitiveness. Industry competitiveness is the biggest bottleneck for China to improve the international competitiveness![Kulturmacht Ohne Kompass: Deutsche Auswartige Kulturbeziehungen Im 20. Jahrhundert (German Edition) [2013] - Original PDF](https://dl.libsan.ir/images/1/12/7_6468e9d0ef5c1.jpg)
![International Summitry and Global Governance: The rise of the G7 and the European Council, 1974-1991 (Cold War History)[2014] - Original PDF](https://dl.libsan.ir/images/1/12/4_6468e7639516a.jpg)
International Summitry and Global Governance: The rise of the G7 and the European Council, 1974-1991 (Cold War History)[2014] - Original PDF
نویسندگان: خلاصه: International Summitry and Global Governance: The rise of the G7 and the European Council, 1974-1991 (Cold War History) 1st Edition by Emmanuel Mourlon-Druol (Editor), Federico Romero (Editor)
The Endogenous Energy-Saving Technological Change in China’s Industrial Sector - Original PDF
نویسندگان: خلاصه: Preface Decarbonization of the Chinese economy largely depends on the degree of decar- bonization of industry. Since improving energy efficiency and increasing energy R&D investment are arguably the chief drivers of the sustainable growth of the Chinese industry, this book attempts to study energy efficiency and energy R&D investment under one normalized economic model. By distinguishing between energy R&D investment and non-energy R&D investment and drawing on the paradigm of neoclassical economics, I start by clarifying the basic concept of energy- saving technological change (hereinafter referred to as “ESTC”) and the related endogenous mechanism, proceed to integrate under the existing endogenous growth model two different mechanisms whereby R&D heterogeneity affects energy effi- ciency, namely the effect of factor substitution and the effect of increased effective energy input, and finally build a framework of analysis and a mathematical model of R&D heterogeneity-based endogenous ESTC in industry. I analyze the model with the tools of competitive equilibrium, centrally planned equilibrium, and numerical simulation and empirically test the major assumptions of the model with industrial statistics and econometric analytical tools, namely the mixed data regression model, the panel data regression model, and the dynamic panel data regression model. This book focuses on how R&D heterogeneity influences endogenous ESTC in China’s industrial sectors and endeavors to answer the following questions: How does R&D heterogeneity bring about endogenous ESTC? How are the rates of ESTC in the industrial sectors estimated? What is the impact of R&D heterogeneity on the rates of ESTC in the industrial sectors? This book sets itself apart from other existing research by the following work and potentially innovative points
HE ROUTLEDGE HANDBOOK OF ACCOUNTING ETHICS - Original PDF
نویسندگان: خلاصه: 1 INTRODUCTION Eileen Z. Taylor and Paul F. Williams “Ethics” and “morals” are two terms about which there is ambiguity. Some scholars consider the terms to be synonymous. Others make a distinction that ethics pertains to right conduct vis-à-vis others, while morals pertains to one’s personal sense of right conduct; still others reverse that distinction. Philosophers tend to regard the distinction between “ethics” and “morals” to be that ethics pertains to a centuries-old conversation about how we decide what is good and bad, right and wrong, while morals is the content of good and bad, right and wrong. The perspective on “ethics” taken in this book is this latter sense; thus the title Companion to Accounting Ethics. The book’s purpose is not to be a handbook of accounting rights and wrongs but rather a collec- tion of conversations employed by educators to assist students of accounting to become more attuned to accounting’s ethical aspects and to become more critical thinkers about the ethical complexities of the function of accounting in human society. As a social science, accounting is the creation of people, for the purpose of accounting for transactions (generally monetary) between and among groups of people. Accounting does not exist without people, and its rules of the day are determined by people; it is mutable and wholly dependent on both the decisions made by people with economic power and acceptance of those decisions by those same people. Similarly, ethics are enacted by people, and the ethicality of an action is determined by the individual affected by the action, as well as by the collective societal acceptance or rejection of an action. Accounting, because it is people driven, inherently has an ethical component. Every deci- sion about how to account for a transaction at some point affects an individual, either directly or indirectly. For example, decisions about recording revenue affect those whose income is commission-based. Decisions about recording an expense affects taxes paid (and received by the government for the benefit of society). Our primary goal with this book is to call attention to the intersectionality of accounting and ethics and to encourage students and researchers to consider the ethical implications of accounting decisionsآیا کتاب مورد نظر هنوز بر روی سایت قرار نگرفته است؟ جای نگرانی نیست! کافی است بر روی گزینه سفارش کتاب کلیک کرده و درخواست خود را ثبت کنید. در کمتر از چند ساعت کتاب شما را آماده خواهیم کرد.