موضوعات
آموزش و پرورش
ادبیات و زبان
پزشکی، دندانپزشکی و داروسازی
تاریخ و جغرافیا
داستان و رمان
دیگر
دین و فلسفه
روانشناسی
ریاضیات و آمار
سلامتی، تناسب اندام و رژیم غذایی
شیمی و پلیمر
علوم اجتماعی و حقوق
علوم زیستی و بیوتکنولوژی
فیزیک و نجوم
کامپیوتر و اینترنت
کتابهای کودکان و داستان
کسب و کار و اقتصاد
کشاورزی و دامپزشکی و غذا
معماری
مهندسی و فناوری
هنر و تئاتر
محصولات
Surely you're joking, Mr. Feynman (bad typesetting) - Original PDF
نویسندگان: خلاصه: A series of anecdotes shouldn't by rights add up to an autobiography, but that's just one of the many pieces of received wisdom that Nobel Prize-winning physicist Richard Feynman (1918-88) cheerfully ignores in his engagingly eccentric book, a bestseller ever since its initial publication in 1985. Fiercely independent (read the chapter entitled "Judging Books by Their Covers"), intolerant of stupidity even when it comes packaged as high intellectualism (check out "Is Electricity Fire?"), unafraid to offend (see "You Just Ask Them?"), Feynman informs by entertaining. It's possible to enjoy Surely You're Joking, Mr. Feynman simply as a bunch of hilarious yarns with the smart-alecky author as know-it-all hero. At some point, however, attentive readers realize that underneath all the merriment simmers a running commentary on what constitutes authentic knowledge: learning by understanding, not by rote; refusal to give up on seemingly insoluble problems; and total disrespect for fancy ideas that have no grounding in the real world. Feynman himself had all these qualities in spades, and they come through with vigor and verve in his no-bull prose. No wonder his students - and readers around the world - adored him.
Miracle Cure - Epub + Converted PDF
نویسندگان: خلاصه: In a clinic on Manhattan's Upper West Side, a doctor has dedicated his life to eradicating a devastating disease. One by one, his patients are getting well. And one by one, they're being targeted by a serial killer. There's only one cure, but many ways to die...
Veterinary Immunology 10E - Original PDF
نویسندگان: خلاصه: This textbook was first published in 1977, at a time when veterinary immunology was relatively new and poorly understood. Nevertheless, it was recognized, even then, that immunology held the key to many of the significant issues in veterinary medicine. The importance of immunology has not declined since then, except among those tasked with establishing college curricula. The decline in basic science instruction at colleges of veterinary medicine in favor of more clinical training has resulted in graduating a generation of veterinarians whose knowledge of immunology is minimal. Yet immunology continues to be a key science. It is central to our understanding of major veterinary issues such as vaccination, cancer, infectious diseases, and allergies. It has been tempting to dilute the contents of this text and its associated website to conform to current curricular trends. I have resisted this. Because the amount of knowledge of immunology required to obtain a veterinary degree has been progressively reduced, the need to document the science in depth has correspondingly increased. This book therefore continues to grow as the result of opening up new, exciting areas of the science. Veterinarians need to know much of this if they are to practice cutting-edge science in the 21st century. Read it, study it, and enjoy its wonderful complexity. Over the many years that this textbook has been published we have seen many changes in the science of immunology. In most cases, these changes have been gradual in nature as investigators add detail to existing knowledge. Occasionally, however, major leaps are made that effectively revolutionize the discipline—socalled paradigm shifts. For example, in the late 1990s, the concept of innate immunity was accepted. Inflammation and other processes were finally recognized as being essential components of the immune system and the dual innate and adaptive immune systems were shown to complement each other. It is interesting to note that this was not a new discovery but a new way of looking at well recognized processes. This new edition also reflects revolutionary changes in the way we think of immunology. Like the concept of innate immunity, these changes are not a result of a previously unknown process but a belated recognition of something known about since the dawn of microbiology, the body's normal microbiota. New methodologies and intensive studies have revealed that many body processes, especially immunity, are regulated by the diverse microbiota that colonizes all body surfaces. Much of immunology has had to be reassessed in the light of this new knowledge. Both innate and adaptive immunity are regulated by those organisms, especially bacteria, that live in the intestine and respiratory tract and on the skin. Many previously unexplained phenomena have now been shown to depend on the normal microbiota. As a result of this new information, the reader will encounter the microbiota at every turn in this book, plus a completely new chapter on the subject. The second new chapter deals with allergic diseases. For many years, these were readily explained by the production of IgE against allergens. The most recent information, however, has demonstrated that allergies are much more complex than this. For example, atopic dermatitis, one of the most common conditions seen by small animal veterinarians, is likely a syndrome with multiple complex causative factors. As a result, allergic and inflammatory diseases deserve a new chapter. These additions cannot, however, hide the fact that the rest of immunology also continues to move forward. Thus the mechanisms by which the body rejects gastrointestinal helminths has been clarified with the discovery of the importance of tuft cells and interleukin-33. Associated with this has been the recognition of the complex nature of innate lymphoid cells and their subpopulations. Some of these advances can be considered routine, such as the identification of new cell surface molecules and many new cytokines. New disease syndromes such as swine SCID, bovine neonatal pancytopenia, and immune-mediated keratoconjunctivitis are now described, and the pathogenesis of others such as atopic dermatitis, type I diabetes mellitus, equine laminitis, and systemic lupus are shown to be more complex than previously believed. New advances in therapy are covered, including the introduction of immune checkpoint therapy in cancer and the use of monoclonal antibody therapy and intravenous immunoglobulin therapy for immune-mediated diseases. The exciting new developments in the use of nanoparticles in vaccines and as adjuvants are now described. The significant roles of vitamins A and D as well as the aryl hydrocarbon receptor in immunity are also recognized. Advances in basic science that are now discussed include new findings on the structure and genetics of bovine antibodies, epigenetics, RNA interference, microRNA, macrophage polarization, and type 1 and type 2 immune responses. I make no apologies for the size and complexity of this text. Immunology is a complex subject that has a direct bearing on many of the most important areas of veterinary medicine. Students, as well as graduate veterinarians, ignore it at their peril. Finally, readers are strongly encouraged to visit the Evolve website for this text. The site is also constantly evolving and improving. In it you will be able to find a collection of more than 450 multiple-choice questions (with the answers!) keyed to each chapter; a set of flashcards also linked to chapters; all the text figures available as PowerPoint slides; and a collection of animations kindly provided by Dr. Abul Abbas, as well as brand new animations created for this textbook, designed to clarify some complex processes and pathways where still figures are inadequate. All the chapter references are keyed to PubMed. There are also new hand-outs that students can print off and use as a reference, should you wish. It is my hope that these assets will help you remain current in this rapidly expanding and exciting field.
Principles of Tissue Engineering Fifth Edition - Original PDF
نویسندگان: خلاصه: Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production – is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field.
Mechanics and Analysis of Composite Materials - Original PDF
نویسندگان: خلاصه: This book is concerned with the topical problems of mechanics of advanced composite materials whose mechanical properties are controlled by high-strength and high-stiffness continuous fibers embedded in polymeric, metal, or ceramic matrix. Although the idea of combining two or more components to produce materials with controlled properties has been known and used from time immemorial, modern composites have been developed only several decades ago and have found by now intensive application in different fields of engineering, particularly, in aerospace structures for which high strength-to-weightand stiffnessto-weight ratios are required.
ALICE'S ADVENTURES IN WONDERLAND - Original PDF
نویسندگان: خلاصه: Al-ice had sat on the bank by her sis-ter till she was tired. Once or twice she had looked at the book her sis-ter held in her hand, but there were no pict-ures in it, "and what is the use of a book," thought Alice, "with-out pict-ures?" She asked her-self as well as she could, for the hot day made her feel quite dull, if it would be worth while to get up and pick some dai-sies to make a chain. Just then a white rab-bit with pink eyes ran close by her. image That was not such a strange thing, nor did Alice think it so much out of the way to hear the Rab-bit say, "Oh dear! Oh, dear! I shall be late!" But when the Rab-bit took a watch out of its pock-et, and looked at it and then ran on, Al-ice start-ed to her feet, for she knew that was the first time she had seen a Rab-bit with a watch. She jumped up and ran to get a look at it, and was just in time to see it pop down a large rab-bit hole near the hedge. As fast as she could go, Al-ice went down the hole af-ter it, and did not once stop to think how in the world she was to get out. The hole went straight on for some way and then turned down with a sharp bend, so sharp that Al-ice had no time to think to stop till she found her-self fall- ing in what seemed a deep well. She must not have moved fast, or the well must have been quite deep, for it took her a long time to go down, and as she went she had time to look at the strange things she passed. First she tried to look down and make out what was there, but it was too dark to see; then she looked at the sides of the well and saw that they were piled with book-shelves; here and there she saw maps hung on pegs. She took down a jar from one of the shelves as she passed. On it was the word Jam, but there was no jam in it, so she put it back on one of the shelves as she fell past it.![Forex Price Action Scalping: an in-depth look into the field of professional scalping[2011] - Original PDF](https://dl.libsan.ir/images/1/12/5_647ece42561ed.jpg)
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