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Preface vi Acknowledgements vi Abbreviations and definitions vii About the companion website viii Section I Introductory Bacteriology 1. Structure of bacterial cells 2 2. Cultivation, preservation and inactivation of bacteria 4 3. Bacterial genetics and genetic variation 6 4. Molecular diagnostic methods 10 5. Laboratory diagnosis of bacterial disease 12 6. Molecular subtyping of bacteria 14 7. Antibacterial agents 18 8. Antimicrobial susceptibility testing 20 9. Bacterial resistance to antimicrobial drugs 22 10. Bacterial infections 24 11. Structure and components of the immune system 26 12. Adaptive immunity 30 13. Protective immune responses against infectious agents 32 Section II Pathogenic Bacteria 14. Staphylococcus species 36 15. Streptococci 38 16. Corynebacterium species and Rhodococcus equi 40 17. Actinobacteria 42 18. Listeria species 46 19. Erysipelothrix rhusiopathiae 47 20. Bacillus species 48 21. Clostridium species 50 22. Mycobacterium species 54 23. Enterobacteriaceae 58 24. Pseudomonas aeruginosa 62 25. Burkholderia mallei and Burkholderia pseudomallei 63 26. Actinobacillus species 64 27. Pasteurella species, Mannheimia haemolytica and Bibersteinia trehalosi 66 28. Histophilus, Haemophilus and Avibacterium species 68 29. Taylorella equigenitalis 70 30. Moraxella bovis 71 31. Francisella tularensis 72 32. Lawsonia intracellularis 73 33. Bordetella species 74 34. Brucella species 76 35. Campylobacter species 80 36. Spirochaetes 82 37. Pathogenic, anaerobic, non-spore-forming Gram-negative bacteria 86 38. Mycoplasmas 88 39. Chlamydiae 92 40. Rickettsiales and Coxiella burnetii 94 Section III Mycology 41. General features of fungi associated with disease in animals 98 42. Dermatophytes 100 43. Aspergillus species 102 44. Yeasts and disease production 104 45. Dimorphic fungi 106 46. Zygomycetes of veterinary importance 108 47. Mycotoxins and mycotoxicoses 110 48. Pathogenic algae and cyanobacteria 114 49. Antifungal chemotherapy 116 Section IV Viruses and Prions 50. Nature, structure and taxonomy of viruses 120 51. Replication of viruses 122 52. Laboratory diagnosis of viral disease 126 53. Antiviral chemotherapy 128 54. Herpesviridae 132 55. Papillomaviridae 136 56. Adenoviridae 138 57. Poxviridae 140 58. Asfarviridae 142 59. Bornaviridae 143 60. Parvoviridae 144 61. Circoviridae 146 62. Astroviridae 147 63. Retroviridae 148 64. Reoviridae 152 65. Orthomyxoviridae 154 66. Paramyxoviridae 156 67. Rhabdoviridae 160 68. Bunyaviridae 162 69. Birnaviridae 163 70. Picornaviridae 164 71. Caliciviridae 166 72. Coronaviridae 168 73. Arteriviridae 170 74. Togaviridae 171 75. Flaviviridae 172 76. Prions 176 Section V Prevention and Control of Infectious Disease 77. Biosecurity 180 78. Vaccination 184 79. Disinfection 188 Appendix: relevant websites 190 Index 191

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