لایب سان

Ebook details:
عنوان: Fundamental Molecular Biology
نویسنده: Lizabeth A. Allison
ناشر: English
زبان: 9781118059814
شابک: 978-1118059814, 1118059816
حجم: 50 Mb
فرمت: True Pdf

Copyright; Brief Contents; Contents; Preface; Chapter 1: The Beginnings of Molecular Biology; 1.1: Introduction; 1.2: Insights into the nature of the heredity material; Mendel's laws of inheritance; The chromosome theory of inheritance; The transforming principle is DNA; Creativity in approach leads to the one gene-one enzyme hypothesis; The importance of technological advances: the Hershey-Chase experiment; 1.3: A model for the structure of DNA: the DNA double helix; 1.4: The central dogma of molecular biology; 1.5: An evolutionary framework for heredity; Chapter summary. Analytical questionsBibliography; Chapter 2: The Structure of DNA; 2.1: Introduction; 2.2: Primary structure: the components of nucleic acids; Five-carbon sugars; Nitrogenous bases; The phosphate functional group; Nucleosides and nucleotides; Nomenclature of nucleotides; The length of RNA and DNA chains; Significance of 5 ́and 3;́ 2.3: Secondary structure of DNA; Hydrogen bonds form between the bases; Base stacking provides chemical stability to the DNA double helix; Structure of the Watson-Crick DNA double helix; Distinguishing between features of alternative double-helical structures. DNA can undergo reversible strand separation2.4: Unusual DNA secondary structures; Slipped structures; Cruciform structures; Triple helix DNA; Disease box 2.1: Friedreich's ataxia and triple helix DNA; 2.5: Tertiary structure of DNA; Supercoiling of DNA; What is the significance of supercoiling in vivo?; Chapter summary; Analytical questions; Bibliography; Chapter 3: The Versatility of RNA; 3.1: Introduction; 3.2: RNA is involved in a wide range of cellular processes; 3.3: Structural motifs of RNA; Secondary structure of RNA; tRNA structure: important insights into RNA structural motifs. Common tertiary structure motifs in RNAKinetics of RNA folding; 3.4: The discovery of RNA catalysis; Tetrahymena self-splicing RNA; Focus box 3.1: The RNA World; RNase P is a ribozyme; Ribozymes catalyze a variety of chemical reactions; 3.5: RNA-based genomes; Eukaryotic RNA viruses; Retroviruses; Disease box 3.1: Avian flu and swine flu; Viroids and other subviral pathogens; Chapter summary; Analytical questions; Bibliography; Chapter 4: Protein Structure and Folding; 4.1: Introduction; 4.2: Primary structure: amino acids and the genetic code; The 22 amino acids found in proteins. Protein primary structureTranslating the genetic code; The 21st and 22nd genetically encoded amino acids; Modified nucleotides and codon bias; D- and L-amino acids in nature; 4.3: The three-dimensional structure of proteins; Secondary structure; Tertiary structure; Quaternary structure; 4.4: Protein function and regulation of activity; Enzymes are biological catalysts; Regulation of protein activity by post-translational modifications; Allosteric regulation of protein activity; Macromolecular assemblages; 4.5: Protein folding and misfolding; Molecular chaperones.

برای ارسال نظر لطفا وارد شوید یا ثبت نام کنید